Synthesis of new 1,3-thiazoline-2-thiones as potential antimycobacterial agents

Document Type : Original Article

Abstract

As a continuation of our efforts in developing new antimycobacterial agents, a series of new 1,3-thiazolidine-2-thione derivatives were synthesized. The chemical structures of the compounds were elucidated by FT-IR, 1H-NMR and Mass spectra. The analysis of theoretical toxicity risks,drug-likeness and drug-score for these series using Osiris program showed acceptable results.

Keywords

• Tuberculosis
• Mycobacterium
• 1
• 3-thiazolidine-2-thione

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